Biochemistry @ Muhlenberg

BCM 441 Advanced Biochemistry

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Author: John Hanna

BCM441

Gaucher’s Disease Type 1

Posted on April 25, 2018 by John Hanna

Author: John Hanna Gaucher’s Disease Type 1 is a rare disease that is characterized by an abnormal buildup of a cellular component called glucosylceramide. Particularly, glucosylceramide can…

BCM441

A Shared 3D Conformation Between Alzheimer, Parkinson and Huntington Oligomers Impairs Ubiquitin-Dependent Proteasome Function

Posted on April 1, 2018 by John Hanna

Author: John Hanna Opposing allosteric controls between two allosteric modulators-HbYX motif and A11 oligomers- that bind to distinct sites on the 20S proteasome. Name of…

BCM441

Omega-3 Docosahexaenoic Fatty Acid Kills Breast Cancer Cells: Unraveling the Complex Pathway that Triggers Cancer Apoptosis Induced by N-3 DHA PolyUnsaturated Fatty Acid

Posted on February 12, 2018 by John Hanna

Author: John Hanna Scheme summarizing the DHA induction of OSGIN1-mediated the onset of apoptosis via the up-regulation of PI3K/Akt/Nrf2 signaling pathway in breast cancer cells…

BCM441

Reflection Blog 2

Posted on February 7, 2018 by John Hanna

Author: John Hanna One of the many perils of studying biochemistry is that we get to navigate the complexity of life from both “bottom-up” and…

BCM441

The role of fatty acid β-oxidation in lymphangiogenesis

Posted on January 24, 2018 by John Hanna

Acetyl-CoA has long been known for its importance as a metabolic intermediate for many pathways. For example, this intermediate can be used in anabolic pathways…

BCM441

My Choice in Biochemistry

Posted on January 22, 2018January 23, 2018 by John Hanna

Biochemistry is the study of vital chemical processes and applications in biological living systems. It allows us to understand the physiology of organisms at the biomolecular…

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This site aggregates the scholarly work of students enrolled in BCM 441 at Muhlenberg College with Dr. Keri Colabroy. Students blog on the latest, high-impact science and explore the mechanism of human disease in depth.

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