I’ve chosen cholera as my topic because it is one of the epidemics that is still plaguing many of the world’s developing nations despite its well understood mode of transmission. Although it is relatively easy to treat with the advent of vaccines, it is important to note that epidemics are difficult to control. I’ve divided my findings into genetics, disease mechanism, public health, and research on treatments. The major themes of research in cholera have been discovering its bacterial nature, assessing its mode of transmission, and establishing healthcare protocols in case of epidemics. Recent focus has been on genetics of cholera because new strains have been appearing that are resistant to antibacterials. In addition, new vaccines that are both more effective, less costly, and more easily reproduced. In addition weighing the benefits and downsides of producing vaccines that protect for a long amount of time but require more upkeep rather than less coverage but single dose vaccines are a hot topic in cholera treatments. Although we know how the bacteria get into the system, the mechanisms that allow its survival are not all understood. New findings suggest that the bacteria are able to extract what they need from the host cell that allow them to turn on their toxicity. Overall, the trends are about containment of cholera epidemics, trying to spread public knowledge about its mode of transmission, and finding new ways to attack and prevent it.
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