Tuberculosis or Atherosclerosis or Hepatitis C

After brainstorming for few minutes, I decided to step away from randomness. So, I have picked three diseases that were somehow popular in my time. Before I started working at the hospital, I was asked to get tested for TB. The first few seconds I was trying to overcome the image of the needle in my head but all have passed by and luckily I have done my first TB test. TB is a disease caused by Mycobacterium tuberculosis (Mtb), a bacterium that spreads in the air from one person to another. The bacteria exit the oral cavity when a person with TB disease speaks, coughs, sneezes, etc. So, you are always asked to get a TB test done when hired to work for hospitals because anyone can become a TB victim. Evidently, the study of TB has been a priority for the National Institute of Allergy and Infectious Diseases. TB is one of the major causes of death worldwide. Globally in 2014, an estimated 480,000 people developed multidrug-resistant TB (1). As we all know by now that bacteria develop resistance and this bacterium happen to be one of them. TB is not a little infection, but can be possibly fatal and strong synthetic antibacterial drugs such as fluoroquinolone have been developed (2). If I decide to study TB, I would look into the strategies the bacterium follow to infect the host and overcome the drug resistance and I will look into the process which quinolone antibiotic drugs propose to treat this type of bacteria.

In the next few minutes of brainstorming, it came to my mind that one of my family members was a victim of a heart disease. So, I decided to include a heart disease that is called Atherosclerosis. Atherosclerosis is a disease in which plaque such as cholesterol starts building up overtime inside the walls of the arteries. This kind of buildup is similar to the dental biofilm that grows on your teeth and with time passing can cause serious problems. So, when the buildup happens within the arteries, the individual experiences a heart attack or a stroke and can be fatal. If I happen to pick this disease, I would definitely focus on why certain substances accumulate on the walls of arteries and through that we can find the factor that brings them all together.

Hepatitis A, B, or C, the three are taken into consideration when working at a clinic. Where I work, we see a lot of individuals suffering from either one of them. Nevertheless, I included Hepatitis C because it is different than A and B in the way it is spread and treated. Hepatitis C is caused by a virus that infects the liver. Many people have chronic hepatitis C and investigating the viral process would be a way to completely exterminate the virus.

My final choice would be focusing on TB disease because it is an international safety matter.

 

  1. Fauci, Anthony S. “Diseases and Conditions,Tuberculosis (TB).” National Institutes of Health. U.S. Department of Health and Human Services, 17 Feb. 2012. Web. 08 Feb. 2017.
  2. “Drug-Resistant TB.” Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 17 Jan. 2017. Web. 08 Feb. 2017.

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