Biochemistry @ Muhlenberg

BCM 441 Advanced Biochemistry

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Tag: bcm441sp18

Theme page 3: Future Treatment and Prevention
BCM411

Theme page 3: Future Treatment and Prevention

Posted on April 13, 2018 by Brendan Trafford

Author: Brendan Trafford Almost every treatment attempted to fight MRSA has ended up failing to some extent due to MRSA’s uncanny ability to form resistances.…

BCM411

Theme Pages 2: Antibiotic resistance prevalence in humans, animals and environments around the world

Posted on April 13, 2018 by Brendan Trafford

Author: Brendan Trafford Antibiotic resistance prevalence in humans, animals and environments around the world: MRSA prevalence throughout human populations is broken into two major categories.…

BCM411

Theme Pages 1: History of MRSA and Mechanisms against antibiotics

Posted on April 13, 2018 by Brendan Trafford

Author: Brendan Trafford What is MRSA? MRSA is a methicillin resistant form of the bacterium Staphylococcus aureus. In some ways this name is a little…

BCM441

A Shared 3D Conformation Between Alzheimer, Parkinson and Huntington Oligomers Impairs Ubiquitin-Dependent Proteasome Function

Posted on April 1, 2018 by John Hanna

Author: John Hanna Opposing allosteric controls between two allosteric modulators-HbYX motif and A11 oligomers- that bind to distinct sites on the 20S proteasome. Name of…

APC/C

SUMOylation: Wrestling with the Regulation of APC/C

Posted on March 29, 2018 by Calvin Inners

Author: Calvin Inners The paper can be accessed here: https://www.nature.com/articles/s41467-018-03486-4   The image above depicts the SUMOylation and ubiquitination of ACP/C through its APC4 domain…

BCM441

An E3 ubiquitin ligase is essential for immune homeostasis

Posted on March 24, 2018 by Brandon Eden

Author: Brandon Eden TRIM29, an E3 ubiquitin ligase as depicted in the above figure, tags STING for proteasome-dependent degradation to downregulate the antiviral cystolic DNA…

BCM441

Calcium Imaging; New way to identify AβO targets

Posted on March 23, 2018 by Endonita Hajzeraj

Author: Endonita Hajzeraj AβOs or soluble amyloid β oligomers are recognized by the public as neurotoxins that trigger divergent signaling in neurons. This signaling of…

BCM 441

The Oncogenic Role of USP4, a deubiquitinase, in Melanoma

Posted on March 18, 2018 by Camille Jessica Cunanan

Author: Camille Jessica Cunanan Skin cancer is the most common form of cancer in the United States, surpassing cancers of the breasts and lungs (1).…

BCM 441

The Oncogenic Role of USP4, a deubiquitinase, in Melanoma

Posted on March 18, 2018 by Camille Jessica Cunanan

Author: Camille Jessica Cunanan Skin cancer is the most common form of cancer in the United States, surpassing cancers of the breasts and lungs (1).…

BCM 441

The Oncogenic Role of USP4, a deubiquitinase, in Melanoma

Posted on March 18, 2018 by Camille Jessica Cunanan

Author: Camille Jessica Cunanan Skin cancer is the most common form of cancer in the United States, surpassing cancers of the breasts and lungs (1).…

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This site aggregates the scholarly work of students enrolled in BCM 441 at Muhlenberg College with Dr. Keri Colabroy. Students blog on the latest, high-impact science and explore the mechanism of human disease in depth.

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