Brainstorming Ideas Instead of Studying!!!!

I may or may not have typed “biochemical diseases” into Google before considering the following:

  1. Acute myeloid leukemia- Over the summer, I worked with an oncologist at one of the Lehigh Valley Health Network hospitals reviewing acute myeloid leukemia (AML) cases treated by the hospital network. Through this opportunity, I was able to learn about the clinical implications of the disease-symptoms, diagnosis, treatments, survival, etc- but I neglected to learn about the biochemistry of the disease! I would love to look at AML from a biochemical standpoint and then connect them to the clinical implications I have learned about and maybe even consider new connections.
  2. Schizophrenia- For some reason, I find schizophrenia really fascinating, maybe because I took one neuroscience class junior year. Schizophrenia is a severe mental illness characterized by disordered thinking and behavior with decreased motivation and cognitive deficits in attention and memory1. For the neuroscience class, I wrote a review paper on the characterization of the dopamine receptor and its role in schizophrenia. It would be interesting to further research the dopamine pathway in its relation to the disease.
  3. Celiac Disease- This is for my roommate who informs EVERYONE, EVERYDAY that she is allergic to gluten. Maybe if I research the disease and discover something, I can relay that the information to her (disclaimer: she does not actually have celiac disease, but is gluten intolerant).

 

Reference:

  1. Labrie V, Clapcote SJ, Roder JC. Mutant mice with reduced NMDA-NR1 glycine affinity or lack of d-amino acid oxidase function exhibit altered anxiety-like behaviors. Pharmacology Biochemistry and Behavior. 2009, 91(4), 610-620.

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