Author: Calvin Inners Prostate cancer is one of the most common types of cancer for men in the world. In fact, only lung cancer, breast…
Category: Cancer
Author: Calvin Inners The paper can be accessed here: https://www.nature.com/articles/s41467-018-03486-4 The image above depicts the SUMOylation and ubiquitination of ACP/C through its APC4 domain…
Author: Calvin Inners The human body is just like any incredible complex machine. There are many extraordinary things that we can accomplish. Unfortunately, since our…
Elaine Gersz ChemBio Spotlight #2 Paper: Polysialylation Controls Dendritic Cell Trafficking by Regulation Chemokine Recognition http://science.sciencemag.org/content/351/6269/186 Polysialic acid (PolySia) has been shown to foster cancer…
Craig B. Thompson et. Al Link to the paper Generally, cancer cells contain some metabolic mutation that favors rapid reproduction and the accumulation…
Tyr-94 Phosphorylation, PDP, and the Warburg Effect Besher Tolaymat ChemBio Spotlight Week 6 Paper: Tyr-94 Phosphorylation Inhibits Pyruvate Dehydrogenase Phosphatase 1 and Promotes Tumor Growth…
Zach Zimmerman, Spotlight Week 2 Paper: Identification of the Major Prostaglandin Glycerol Ester Hydrolase in Human Cancer Cells http://www.jbc.org/content/289/49/33741.full Enzyme in a hay stack (if…
Among the cell’s many mechanisms to stop the aberrant cell proliferation characterized in cancer is the activation of Oncogene-induced senescence (OIS), which stops cells from…
