In 2016, BCM 441 Advanced Biochemistry built webpages on the following human diseases: Chronic Granulomatous Disease History and Metabolic Context Molecular Basis of the Disease…
Category: Treatment and Disease management
Zachary Gallagher Chembio spotlight #1 Paper: Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase http://www.jbc.org/content/291/6/2583 GRK-2: A…
By: Ramzy Burns Paper: Bile Acid Receptor Activation Modulates Hepatic Monocyte Activity and Improves Nonalcoholic Fatty Liver Disease http://www.jbc.org/content/288/17/11761.long Stop the Inflammation! The Role of Bile…
Porphyrias are a class of diseases that arise from dysfunctions in any of the eight steps in heme biosynthesis. Specifically, variegate porphyria (VP) is caused…
Paper: Differential stem-and progenitor-cell trafficking by prostaglandin E2. doi:10.1038/nature11929 PGE2[1]: Your Bone Marrow’s Best Babysitter Rebecca Golden Stem cells are un-programmed cells that can develop…
Journal of Biological Chemistry: Ganglioside GM1-mediated transcytosis of cholera toxin bypasses the retrograde pathway and depends on the structure of the ceramide domain Cholera toxin…
Paper: In Cellulo Examination of a β-α Hybrid Construct of β-Hexosamindase A Subunits, Reported to Interact with the GM2 Activator Protein and Hydrolyze GM2 Ganglioside…
Major Depressive disorder (MDD) is a disease that affects…
Phenylketonuria (PKU) is an autosomal recessive genetic disorder that is inherited due to a contribution of the genetic disorder gene from each parent. Phenylketonuria is…
Spotlight #2, Radhika Rani Immunoactivity of Protein Conjugates of Carba Analogues from Neisseria meningitidis A Capsular Polysaccharide ACS Chem. Biol., 2013, 8 (11), pp 2561–2567 http://pubs.acs.org/doi/pdf/10.1021/cb400463u Of the…
