The human body obtains energy through the breakdown of fatty acids, which are often stored as a complex called triacylglycerol. In order to initiate the…
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Enzyme regulation is an important process in controlling metabolic flux. The two ways in which this is thought to happen is by inhibiting an enzyme…
By Evan Gassaway Paper: Metabolic regulation of Nucleo-cytosolic Trafficking of Carbohydrate Response Element-binding Protein (ChREBP): Role of Ketone Bodies http://www.jbc.org/content/288/39/28368 ChREBP (carbohydrate response element-binding protein)…
By Edward Quach Paper: Cohen, T. J. et al. The acetylation of tau inhibits its function and promotes pathological tau aggregation. Nat Com. 2, 252…
By Hudson Roth Spotlight #2 Zheng, H. et al. Biochemistry 2013, 52, 5876-5883. http://pubs.acs.org/doi/pdf/10.1021/bi400821s In recent years there has been an increasing interest in biocatalysis,…
By Ian Smith Paper: Vinylogous chain branching catalysed by a dedicated polyketide synthase module http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12588.html Creating complex naturally-occurring compounds biosynthetically, by mimicking prokaryotic metabolism, is…
