Author: John Hanna Opposing allosteric controls between two allosteric modulators-HbYX motif and A11 oligomers- that bind to distinct sites on the 20S proteasome. Name of…
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Author: Brandon Eden TRIM29, an E3 ubiquitin ligase as depicted in the above figure, tags STING for proteasome-dependent degradation to downregulate the antiviral cystolic DNA…
Author: Calvin Inners This figure is taken from the Castaño-Rodríguez et al. paper. In part C, it shows the connection between different bacteria present in…
Blood is the one relationship we can never end. If you and blood decide to call it quits and go your separate ways here and…
Endothelial cells line the interior surface of blood and lymphatic vessels and are responsible for the formation of new blood vessels, a process known as…
When I first started declared my major freshman year, I received so many question asking what did studying biochemistry actually entail. Naturally, I had no…
January 18, 2017. Mark your calendars. This is the day I officially appreciate PyMOL more after using Swiss PDB Viewer. All I need is a…
Tyler Florio’s Blog Spotlight – Ubiquitination independent of E1 and E2 enzymes by bacterial effectors Link: http://www.nature.com.muhlenberg.idm.oclc.org/nature/journal/vaop/ncurrent/full/nature17657.html Ubiquitination is a vital cellular process universally observed…
Tyler Gottlieb March 25, 2016 ChemBio Spotlight #5 Paper: Imbalanced OPA1 Processing and Mitochondrial Fragmentation Cause Heart Failure in Mice http://science.sciencemag.org/content/350/6265/aad0116.full Mitochondria, Stress, and Your…
Stephanie Spiegel ChemBio Spotlight #4 Paper: PKD1 Inhibits AMPK2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells http://www.jbc.org/content/291/11/5664.full.pdf+html Whodunit? –…
