Zachary Gallagher Chembio spotlight #1 Paper: Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase http://www.jbc.org/content/291/6/2583 GRK-2: A…
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Essig A et al. 2014. Copsin, a novel peptide-based fungal antibiotic interfering with the peptidoglycan synthesis. Journal of Biological Chemistry. 289 (50): 34953-34964. doi: 10.1074/jbc.M114.599878 Antibiotics have…
Nuclear Enrichment of Folate Cofactors and Methylenetetrahydrofolate Dehydrogenase 1 (MTHFD1) Protect de novo Thymidylate Biosynthesis during Folate Deficiency by: Martha S. Field, Elena Kamynina, Olufunmilayon…
Craig B. Thompson et. Al Link to the paper Generally, cancer cells contain some metabolic mutation that favors rapid reproduction and the accumulation…
Paper: Aguilar-Arnal, L., Katada, S., Orozco-Solis, R., and Sassone-Corsi, R. “NAD+-SIRT1 Control of H3K4 Trimethylation through Circadian Deacetylation of MLL1.” Nature Structural & Molecular Biology,…
Ryan Ferrie ChemicalBio 441 Week 9 Blog Spotlight…
Tyr-94 Phosphorylation, PDP, and the Warburg Effect Besher Tolaymat ChemBio Spotlight Week 6 Paper: Tyr-94 Phosphorylation Inhibits Pyruvate Dehydrogenase Phosphatase 1 and Promotes Tumor Growth…
The paper that I chose to focus on is called “Farnesyltransferase Haplodeficiency Reduces Neuropathology and Rescues Cognitive Function in a Mouse Model of Alzheimer Disease.”…
Paper: The p38 Pathway Regulates Oxidative Stress Tolerance by Phosphorylation of Mitochondrial Protein IscU In this paper, the authors examined the role of the P38-mitogen…
Kelly Cann ChemBio Spotlight Week 3 Paper:The Interplay of Protein Kinase A and Perilipin 5 Regulates Cardiac Lipolysis Getting to the Heart of the Matter:…
