Nikki Bilgram ChemBio Spotlight #3 Paper: Catalytic Mechanism of a Retinoid Isomerase Essential for Vertebrate Vision http://www.nature.com/nchembio/journal/v11/n6/full/nchembio.1799.html RPE65 is a membrane-bound retinoid isomerase that is…
Elaine Gersz ChemBio Spotlight #2 Paper: Polysialylation Controls Dendritic Cell Trafficking by Regulation Chemokine Recognition http://science.sciencemag.org/content/351/6269/186 Polysialic acid (PolySia) has been shown to foster cancer…
Zachary Gallagher Chembio spotlight #1 Paper: Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase http://www.jbc.org/content/291/6/2583 GRK-2: A…
Everyone knows that mitochondria are the powerhouse of the cell. However, mitochondria are also involved in a variety of cellular processes such as amino acid…
Essig A et al. 2014. Copsin, a novel peptide-based fungal antibiotic interfering with the peptidoglycan synthesis. Journal of Biological Chemistry. 289 (50): 34953-34964. doi: 10.1074/jbc.M114.599878 Antibiotics have…
Nuclear Enrichment of Folate Cofactors and Methylenetetrahydrofolate Dehydrogenase 1 (MTHFD1) Protect de novo Thymidylate Biosynthesis during Folate Deficiency by: Martha S. Field, Elena Kamynina, Olufunmilayon…
Craig B. Thompson et. Al Link to the paper Generally, cancer cells contain some metabolic mutation that favors rapid reproduction and the accumulation…
Paper: Aguilar-Arnal, L., Katada, S., Orozco-Solis, R., and Sassone-Corsi, R. “NAD+-SIRT1 Control of H3K4 Trimethylation through Circadian Deacetylation of MLL1.” Nature Structural & Molecular Biology,…
Ryan Ferrie ChemicalBio 441 Week 9 Blog Spotlight…
Tyr-94 Phosphorylation, PDP, and the Warburg Effect Besher Tolaymat ChemBio Spotlight Week 6 Paper: Tyr-94 Phosphorylation Inhibits Pyruvate Dehydrogenase Phosphatase 1 and Promotes Tumor Growth…
