The paper that I chose to focus on is called “Farnesyltransferase Haplodeficiency Reduces Neuropathology and Rescues Cognitive Function in a Mouse Model of Alzheimer Disease.”…
Paper: The p38 Pathway Regulates Oxidative Stress Tolerance by Phosphorylation of Mitochondrial Protein IscU In this paper, the authors examined the role of the P38-mitogen…
Kelly Cann ChemBio Spotlight Week 3 Paper:The Interplay of Protein Kinase A and Perilipin 5 Regulates Cardiac Lipolysis Getting to the Heart of the Matter:…
Zach Zimmerman, Spotlight Week 2 Paper: Identification of the Major Prostaglandin Glycerol Ester Hydrolase in Human Cancer Cells http://www.jbc.org/content/289/49/33741.full Enzyme in a hay stack (if…
Article: Transcripts involved in calcium signaling and telencephalic neuronal fate are altered in induced pluripotent stem cells from bipolar disorder patients. (Chen, et al. 2014)…
By: Ramzy Burns Paper: Bile Acid Receptor Activation Modulates Hepatic Monocyte Activity and Improves Nonalcoholic Fatty Liver Disease http://www.jbc.org/content/288/17/11761.long Stop the Inflammation! The Role of Bile…
Adrenoleukodystrophy (X-ALD) is an X-linked disorder that causes severe neurodegeneration. The hallmark of X-ALD is an accumulation of very long chain fatty acids (VLCFA) in…
Porphyrias are a class of diseases that arise from dysfunctions in any of the eight steps in heme biosynthesis. Specifically, variegate porphyria (VP) is caused…
Paper: Differential stem-and progenitor-cell trafficking by prostaglandin E2. doi:10.1038/nature11929 PGE2[1]: Your Bone Marrow’s Best Babysitter Rebecca Golden Stem cells are un-programmed cells that can develop…
Journal of Biological Chemistry: Ganglioside GM1-mediated transcytosis of cholera toxin bypasses the retrograde pathway and depends on the structure of the ceramide domain Cholera toxin…
