Zach Zimmerman, Spotlight Week 2 Paper: Identification of the Major Prostaglandin Glycerol Ester Hydrolase in Human Cancer Cells http://www.jbc.org/content/289/49/33741.full Enzyme in a hay stack (if…
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Article: Transcripts involved in calcium signaling and telencephalic neuronal fate are altered in induced pluripotent stem cells from bipolar disorder patients. (Chen, et al. 2014)…
By: Ramzy Burns Paper: Bile Acid Receptor Activation Modulates Hepatic Monocyte Activity and Improves Nonalcoholic Fatty Liver Disease http://www.jbc.org/content/288/17/11761.long Stop the Inflammation! The Role of Bile…
Adrenoleukodystrophy (X-ALD) is an X-linked disorder that causes severe neurodegeneration. The hallmark of X-ALD is an accumulation of very long chain fatty acids (VLCFA) in…
Porphyrias are a class of diseases that arise from dysfunctions in any of the eight steps in heme biosynthesis. Specifically, variegate porphyria (VP) is caused…
Paper: Differential stem-and progenitor-cell trafficking by prostaglandin E2. doi:10.1038/nature11929 PGE2[1]: Your Bone Marrow’s Best Babysitter Rebecca Golden Stem cells are un-programmed cells that can develop…
Journal of Biological Chemistry: Ganglioside GM1-mediated transcytosis of cholera toxin bypasses the retrograde pathway and depends on the structure of the ceramide domain Cholera toxin…
Paper: In Cellulo Examination of a β-α Hybrid Construct of β-Hexosamindase A Subunits, Reported to Interact with the GM2 Activator Protein and Hydrolyze GM2 Ganglioside…
Major Depressive disorder (MDD) is a disease that affects…
Cocaine is a highly addictive recreational drug, traditionally extracted from the coca plant grown in south America and more recently Columbia. This drug was commonly used…
